The role of Gynostemma extract in skin care

Gynostemma pentaphyllum extract has the functions of strengthening the body, enhancing physical fitness, activating cells, anti-fatigue, anti-ulcer, anti-aging, lowering blood pressure, lowering blood fat, anti-cancer, brain-soothing, improving liver function, treating hair loss, moisturizing skin, beauty and weight loss, etc. a function.


It has the effect of ginseng, and there is no toxic side effect of overdose of ginseng. my country has included the development of Gynostemma pentaphyllum in the Spark Program of the State Science and Technology Commission. Today, I will briefly introduce the functions of Gynostemma pentaphyllum in anti-oxidation, weight loss, and beauty and skin care.

Pharmacological studies have shown that Gynostemma Gynostemma saponins and their hydrophilic effective parts have a variety of physiological activities. Combined with excess fat in the human body, they can significantly reduce serum cholesterol, triglycerides, and low-density lipoprotein, and can also significantly increase. Anti-atherosclerotic substance - high-density lipoprotein, can regulate fat metabolism, inhibit the decomposition of fat by adipocytes caused by adrenocorticotropin and the function of converting glucose into fat, and it is useful for the prevention and treatment of atherosclerosis. and immunosuppression have significant curative effect.

Gynostemma pentaphyllum extract can inhibit the proliferation of more than 20 kinds of cancer cells, and the effect can reach 20% to 80%. It also has a significant effect on gray and black hair. According to Japanese Patent (No. 99417, 1985), daily dose of Gynostemma (dry product) 0.1-9.0 g can reduce or completely disappear after 3 months of white hair; apply Gynostemma extract solution to the affected area with water or alcohol, and the same effect can also be obtained .


Suppress obesity and regulate fat metabolism

The effect of Gynostemma pentaphyllum on reducing blood lipids and inhibiting obesity is related to its inhibition of the production of free fatty acids and the synthesis of neutral fats in adipocytes. Gynostemma saponin has its unique superiority in practical performance. Gynostemma saponin can regulate the metabolism of human body fat, inhibit the conversion of glucose into fat, can significantly reduce body weight and reduce the thickness of subcutaneous fat, and can regulate vasoconstriction and relaxation performance, improve The role of blood circulation can be used to develop beauty cosmetics and prevent obesity.

effect on blood sugar

The effect of Gynostemma pentaphyllum on glucose metabolism has attracted people's attention. The research results of Gong Weigui et al. showed that Gynostemma pentaphyllum can prevent senile diabetes. Clinical application of Gynostemma pentaphyllum to prevent and treat senile diabetes has achieved certain results, which is related to the hypoglycemic effect of Gynostemma saponin and the improvement of glucose tolerance.

Strong, anti-aging effect Antioxidant effect

The activation of cells

Gynostemma pentaphyllum prolongs the cell reproduction passage number of the constituent organisms. When the total glycosides is 200 mg/L in the culture medium, the isolated normal diploid fibroblasts (WI-1) of the human fetus are propagated to 59 passages, while the control group is only passed down. The growth stopped at passage 51, and the growth was prolonged by 15.7%. In vitro culture of skin cells from patients with Werner's syndrome, the control group only propagated for 22 generations, and the Gynostemma group extended to 27 generations, an increase of 22.7%. The cell passaging test shows that Gynostemma pentaphyllum can prolong the lifespan of cells. The lifespan of an organism (including the human body) depends on the lifespan of the most basic unit of the organism, the cell. Therefore, Gynostemma pentaphyllum also has the effect of prolonging the lifespan of cells. .

2. Anti-aging effect

A large number of experiments have shown that Gynostemma pentaphyllum has the effect of anti-aging and prolonging lifespan, and its mechanism is achieved by anti-oxidation and prolonging cell reproduction and passage. Lipid peroxide (LPO) in the body can change biofilms with high lipid content, damage the structure of cellular ribonucleic acid (RNA) and deoxyribonucleic acid (DNA), and cause protein molecules to cross-link, resulting in cellular Aging, tissue damage and lipofuscin deposition, etc. Elimination or reduction of LPO is the premise of maintaining the normal and vigorous metabolism of the body, and Gynostemma Gynostemma can significantly reduce the LPO content in the body. Superoxide dismutase (SOD) is a superoxide radical scavenger in the body and reduces LPO formation. Gynostemma pentaphyllum potently enhances SOD activity. When 4% water extract was added to the feed and fed to 5-month-old mice for 2 months, the SOD activity increased from 21.69±3.08 units in the control group to 33.5±2.90 units; the same batch of other animals Continued feeding to 4 months, the control group all died, while 50% of the animals in the Gynostemma group survived. It shows that Gynostemma saponins can enhance the activity of SOD, degrade LPO, and activate the special structure of the cell itself and its various protective systems. For example, antioxidant enzymes can prevent or interrupt lipid peroxidation to a certain extent. Antioxidant effect achieves the purpose of anti-aging.

Beauty, hair care and black hair effect

Gynostemma has a cosmetic effect, and eating Gynostemma saponins can make the skin moist and elastic. It may be because Gynostemma saponins participate in cell activation, activate metabolism, strengthen blood circulation, and excrete lipids. 


Elderly patients with gastric ulcer taking Gynostemma saponins found that with the improvement of ulcer symptoms, the white hair turned black. The gray hair rate was 25% to 80%, and only about 5% of the white hair remained after treatment. Takemoto Changsong used Gynostemma as a tea for a long time, and the gray hair was reduced. If he took the extract to drink it, he found that some gray hair turned black after 3 months. Japan also reported that the use of Gynostemma extract or granules for 3 months to 1 year can significantly reduce senile white hair, and even turn it all black. Some people use 20 mg of Gynostemma saponin and soybean saponin each, dissolved in drinks such as black tea, and taken every day. After a few months, the hair loss is significantly reduced and the hair grows back. 

One of the reasons why Gynostemma pentaphyllum can cure gray hair is related to its effects on improving scalp microvascular channels, promoting lipid discharge, and enhancing and restoring cell vitality. Gynostemma has a vitamin E-like effect, and the hair pulling force treated with Gynostemma pentaphyllum is significantly stronger than that treated with blank water, and the hair toughness is enhanced. Now Japan has used Gynostemma extract as a hair protectant, such as hair tonic 1000 ml containing Gynostemma 5 mg.


GYNOSTEMMA PENTAPHYLLUM LEAF EXTRACT

Beauty Skin Care Skin Conditioner

Gynostemma pentaphyllum extract is isolated from the plant Gynostemma pentaphyllum, more than 50 species of Gynostemma saponins, and like ginsenosides, belong to the tetracyclic triterpenoid mala saponins. Traditional Chinese medicine believes that Gynostemma pentaphyllum is bitter in taste and cold in nature, and has the functions of clearing away heat and detoxifying, invigorating qi, relieving cough and expectorating phlegm. Broad-spectrum anti-cancer effect. For the skin, it can astringe pores, anti-aging, and enhance the body's immune function.

(1) Improve the microcirculation of the hair, make the cells of the epidermal germinal layer have vigorous metabolism, and enhance the renewal of skin collagen fibers, and can prevent premature graying of hair and treat senile hair loss.

(2) Inhibit cell senescence and prolong cell lifespan. The buildup after scalp cells die form dandruff. The anti-aging effect of Gynostemma saponin can prolong the life of scalp cells, reduce the production of dandruff, and has the function of sterilizing and relieving itching.

(3) Anti-ultraviolet damage, nourish hair. It can prevent the hair from turning yellow and rough due to wind and sun, and is conducive to the repair of hair end damage caused by electric perm, cold perm, hair dyeing, etc., and can make the hair oily, bright, fluffy and soft.

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