Glutathione, also known as GSH, is a 3-peptide consisting of L-glutamic acid, L-cysteine and amino acid that is widely present in animal, plant and microbial cells. GSH can protect cells from ultraviolet rays, heavy metals and a variety of exogenous substances, and also plays an important role in protecting cells from oxidative damage.
Glutathione (GSH) is a drug for the treatment of organic solvent poisoning of meat-substituted aromatic hydrocarbons, unsaturated aliphatic hydrocarbons and epoxides. Glutathione can be combined with it and excreted through biotransformation.
Glutathione is a tripeptide composed of glutamic acid, cystine and glycine. It is a physiological factor with a wide range of physiological functions. It is the prosthetic group of glyceraldehyde phosphate dehydrogenase, and glyoxalase and The coenzyme of triose phosphate dehydrogenase is involved in the tricarboxylic acid cycle and sugar metabolism, enabling the human body to obtain high energy. Glutathione can activate a variety of enzymes, such as sulfhydryl and coenzymes in the body, thereby promoting the metabolism of carbohydrates, fats, and proteins, and affecting the metabolic process of cells. It is an important regulatory metabolite in cells. Reduced glutathione can combine with peroxides and free radicals to prevent the damage of sulfhydryl groups by antioxidants, protect the proteins and enzymes containing sulfhydryl groups in the cell membrane from being damaged, and resist the damage of free radicals to important organs. Glutathione is synthesized in cells, and its metabolism and synthesis are mainly in the liver. It is widely distributed in various organs of the body and plays an important role in maintaining the biological function of cells.
Glutathione is also used as a medicine, such as Altomoran, L-glutathione, L-glutathione reduced, Guladine, reduced glutathione, and green tinol.
The role of glutathione
Glutathione can participate in the reduction of oxygen in the body. Under the action of glutathione transferase, it can combine with peroxides and free radicals to prevent the damage of sulfhydryl groups by antioxidants, and protect sulfhydryl-containing proteins in cell membranes. Sulfhydryl enzymes are not destroyed. It is used for the rescue of poisoning of heavy metals, organic solvents, acetaminophen, etc. and the adjuvant treatment of hepatitis and fatty liver. Ophthalmology is also used for cataracts, keratitis, corneal ulcers and other eye diseases.
(1) Detoxification: It has a detoxification effect on poisoning such as acrylonitrile, fluoride, carbon monoxide, heavy metals, organic solvents and acetaminophen (acetaminophen), etc., has a protective effect on the red blood cell membrane, can prevent hemolysis, reduce methemoglobin .
(2) It has a protective effect on certain injuries: it can improve the symptoms of leukopenia caused by radiation sickness and anti-tumor therapy.
(3) Liver protection, anti-allergy, treatment of respiratory distress syndrome, etc.
(4) Improve adverse reactions such as rash, stomach pain, nausea, and vomiting, and the injection site can be slightly painful.
The role of glutathione
1. Protect the liver: This medicine can inhibit the formation of fatty liver, and has the effect of improving symptoms and signs and restoring the liver and liver for a variety of liver diseases such as alcoholic hepatitis, drug-induced hepatitis, viral hepatitis and infectious liver disease.
2. For patients receiving radiation therapy and chemotherapy.
3. Treat hypoxemia. Such as ARDS, acute anemia, sepsis and so on.
4. For the adjuvant treatment of poisons such as organophosphorus, amine or nitro compounds, carbon monoxide, heavy metals and organic solvents.
5. For preventing pigmentation.
6. For the treatment of allergic symptoms caused by the imbalance between acetylcholine and cholinesterase.
7. This medicine eye drop can be used for early senile cataract, corneal ulcer, corneal epithelial peeling, keratitis, etc.
Glutathione Adverse Reactions and Precautions
1. A small number of patients use glutathione
There may be rash, stomach pain, nausea, vomiting, etc. There may be mild pain at the injection site.
2. A small number of patients may experience itching, irritation, eye congestion, transient blurred vision and other symptoms after using this medicine eye drops, which disappear after stopping the medicine.
Contraindications for glutathione use
Those who are allergic to glutathione are disabled.
The adverse effects of glutathione in pregnant and breastfeeding women are unknown.
Comments
Post a Comment